Model year guide

2022 Lexus RX 350

Recalls, most-reported problems, crash-test ratings, fuel economy and what a 2022 Lexus RX 350 is worth — from official NHTSA and EPA data. 362 on record.

2022 Lexus RX 350 — representative photo
Representative photo

2022 Lexus RX 350 at a glance

Safety recallsNone
Owner complaints39
Overall safety4 / 5 ★
Combined23 mpg

Included: that car's specs and build sheet, model-year recall campaigns and a fair price.

2022 Lexus RX 350 recalls 0

No NHTSA safety-recall campaigns are on record for the 2022 Lexus RX 350.

Source: U.S. NHTSA, checked 4 Nov 2026. A campaign covers the model year; to see whether a particular car still needs the repair, check its VIN on NHTSA.gov or ask a franchised dealer.

2022 Lexus RX 350 common problems

The most-reported problem areas across all 39 owner complaints filed with NHTSA — and what to check before you buy.

Electrical System
Test every electrical feature: windows, locks, infotainment, charging and all lights. Watch for flickering, dead accessories or warning lights.
Fuel/propulsion System
Check for fuel or battery warnings, hard starts and stalling. On a hybrid/EV, confirm charging and range behave normally.
Service Brakes
Brakes should feel firm and quiet — no grinding, pulsing or pulling. Check for an ABS light and uneven pad/rotor wear.
Power Train
Drive through every gear: watch for slipping, hard or delayed shifts, and shudder. Check for transmission/driveline leaks and noises.
Engine
Listen for knocks or ticking, check for leaks and blue/white exhaust smoke, and make sure it doesn't overheat. No check-engine light should be on.
Tires
Check tread depth, the DOT age date, and that all four tires match with even wear. Look for bulges or cracks.

2022 Lexus RX 350 safety ratings

Overall★★★★★
Frontal crash★★★★★
Side crash★★★★★
Rollover★★★★★
Frontal — driver★★★★★
Frontal — passenger★★★★★
Side — front seat★★★★★
Side — rear seat★★★★★
Side pole★★★★★

Rollover risk: 16.4% — NHTSA's estimated chance of rollover in a single-vehicle crash (dynamic test: no tip).

Source: NHTSA 5-Star Safety Ratings (NCAP), tested as the 2022 Lexus RX 350 SUV AWD. Ratings can differ by body style and drivetrain.

2022 Lexus RX 350 MPG & running costs

Combined23 mpg
City20 mpg
Highway27 mpg
Est. annual fuel cost$2,900
EPA size classSmall Sport Utility Vehicle 2WD
TransmissionAutomatic (S8)
5-yr fuel cost vs average new car$2,500 more

Source: U.S. EPA / DOE fueleconomy.gov.

Estimated 5-year cost to own

A rough guide to what running a 2022 Lexus RX 350 costs over five years and 75,000 miles.

Fuel (5 yrs)$14,500
Fuel only$14,500
Per mile$0.19

How this is estimated: fuel is the U.S. EPA annual cost at 15,000 miles a year. There aren't enough comparable listings to estimate depreciation for this model, so it is left out. Not included: insurance, maintenance, repairs, taxes, registration and finance costs. Treat it as a comparison guide, not a quote.

Dimensions & weight

Length
192.5 in
Width
74.8 in
Height
67.7 in
Wheelbase
109.8 in
Curb weight
4,453 lb
Front track
64.6 in
Rear track
64.2 in

Manufacturer-reported figures for the 2022 Lexus RX 350. Source: Transport Canada vehicle specifications via NHTSA.

Investigations & service bulletins

Manufacturer service bulletins 85

Technical notes the manufacturer sent to dealers about known issues and fixes. Useful to mention to a mechanic — they are not recalls and repairs may not be covered. Showing the 10 most recent of 85.

OBSOLETE NOTICE February 2, 2026: This bulletin is now obsolete. Please see L-SB-0004-26.

Bulletin L-SB-0057-22 Rev2 · Electrical System · Feb 2026

Some 2018 – 2025 model year Lexus vehicles equipped with the Enform™ 2.0 Navigation System, require a Special Service Tool (SST) USB flash drive to update the map, points of interest, and system software.

Bulletin L-SB-0004-26 · Electrical System · Jan 2026

Some 2005 – 2026 Lexus vehicles that have undergone water intrusion may exhibit a condition in which a musty odor is present. Follow the procedures in this bulletin to remediate the odor and address this condition. The purpose of this Service Bulletin is to pr…

Bulletin L-SB-0030-24 Rev2 · Structure · Dec 2025

Some customers may experience operational difficulties with some telematics features which they cannot resolve on their own. These resources, in conjunction with the Repair Manual, are for dealership personnel to assist those customers with user issues, user e…

Bulletin L-TT-0326-23 Rev2 · Electrical System · Aug 2025

The air conditioning dye injection tool kit has been developed to aid in identifying the location of air conditioning refrigerant leaks. The procedures outlined in this Service Bulletin aid in locating, inspecting, and repairing refrigerant leaks.

Bulletin L-SB-0043-23 Rev1 · Electrical System · Jun 2025

To assist with the early detection and early resolution of audio related concerns you may be asked to recover MMR data from the head unit. The following steps are instructions on how to retrieve the data from the system and are only to be used when requested b…

Bulletin L-TT-0341-25 · Electrical System · Apr 2025

To assist with the early detection and early resolution of audio related concerns you may be asked to recover MMR data from the head unit. The following steps are instructions on how to retrieve the data from the system and are only to be used when requested b…

Bulletin L-TT-0341-25 · Electrical System · Apr 2025

The Immobilizer and Smart Key Reset is a feature that allows the registration of new keys when all master keys are lost. Once the system is reset, all previously registered keys will be erased and can never be reused. Another feature, Add/Remove Key, is also a…

Bulletin L-SB-0013-24 Rev1 · Electrical System · Feb 2025

The Immobilizer and Smart Key Reset is a feature that allows the registration of new keys when all master keys are lost. Once the system is reset, all previously registered keys will be erased and can never be reused. Another feature, Add/Remove Key, is also a…

Bulletin L-SB-0013-24 Rev1 · Electrical System · Feb 2025

Some 2010 – 2026 model year Lexus vehicles may exhibit paint stains after the removal of Rapgard™. The paint stains may appear to be under the clear coat but are usually under wrinkles in the Rapgard™. The wrinkles may trap water and cause the paint to stain f…

Bulletin L-SB-0017-19 Rev1 · Structure · Feb 2025

Source: NHTSA Office of Defects Investigation, listed for the RX 350 FWD. Model-year data, not specific to one car.

About the Lexus RX 350

The Lexus RX is a luxury crossover SUV sold since 1998 by Lexus, a luxury division of Toyota. Originally released in its home market of Japan in late 1997 as the Toyota Harrier, export sales began in March 1998 as the Lexus RX.

From Wikipedia, licensed CC BY-SA 4.0. Describes the model line in general, not this model year specifically.

2022 Lexus RX 350 vehicles on record

Other Lexus RX 350 model years

2022 Lexus RX 350 — frequently asked questions

Does the 2022 Lexus RX 350 have any safety recalls?

NHTSA lists no safety-recall campaigns for the 2022 Lexus RX 350. Whether an individual car still needs a recall repair depends on its VIN — check it on NHTSA.gov or ask a franchised dealer. Recall repairs are done at no charge.

What are the most common problems with the 2022 Lexus RX 350?

Across all 39 owner complaints filed with NHTSA, the most-reported problem areas are electrical system, fuel/propulsion system, service brakes.

What is the 2022 Lexus RX 350 safety rating?

NHTSA gives the 2022 Lexus RX 350 an overall crash-test rating of 4 out of 5 stars (frontal 4★, side 5★, rollover 4★).

What gas mileage does the 2022 Lexus RX 350 get?

The 2022 Lexus RX 350 has a U.S. EPA estimate of 23 mpg combined (20 city / 27 highway).

Sources: NHTSA (recalls, complaints, crash tests), U.S. EPA (fuel economy). Vehicle data only — CarLogs never shows owner information.